منابع مشابه
Myeloid haemopoietic growth factors.
I!. Haemopoietic growth factors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 113 A. lnterleukin 3 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 113 I. Cells which respon.d to interleukin 3 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ....
متن کاملNew therapies Haemopoietic growth factors
Haemopoietic growth factors are involved in the production of the various blood cells from progenitors in the bone marrow, making them useful in a range of clinical situations. The genes for several of them have been cloned and their production engineered by recombinant technology, making them widely available. Myeloid growth factors are used to support patients in the aftermath of chemotherapy...
متن کاملHaemopoietic growth factors and leukaemogenesis.
Haemopoietic stem cells give rise to all the different mature circulating blood cell types by a process of differentiation, proliferation and development. T h e pluripotent haemopoietic stem cells are required throughout the lifespan of an animal because mature cells, such as erythrocytes and neutrophils, are short lived. T h e defining characteristic of the stem cell population is therefore it...
متن کاملMolecular events associated with the action of haemopoietic growth factors.
Haemopoietic growth factors stimulate a number of consensus biochemical and molecular events regardless of the specificity detailed by unique ligand and receptor structures. Analysis of three distinct colony stimulating factors, CSFs (IL-3, G-CSF, GM-CSF) and the lymphocytotropic growth factor IL-2 reveal remarkable similar distal subcellular biochemical signals although initial membrane 'signa...
متن کاملHaemopoietic growth factors--from discovery to clinical application.
The Colony Stimulating Factors (CSFs) are a family of haemopoietic hormones that likely share a common ancestral origin and stimulate white blood cell development. They display unique but overlapping biological functions and stimulate the survival, proliferation, differentiation and functional activation of granulocytes and monocytes/macrophages and their precursor cells in vitro and in vivo. E...
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ژورنال
عنوان ژورنال: BMJ
سال: 1991
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.302.6786.1164